We are working together on our GAMU interdisciplinary project Modeling UFOs
From 2.10. to 4.10. we will host Hil Meijer
Published on Sep 14, 2023
On that occasion, we would like to invite everyone to
Colloquium Fall 2023
Date: Tuesday, October 3
Location: Lecture hall M1
Time: 2 pm
Speaker: Hil Meijer
Title: Data-driven dynamical network models of brain activity in epilepsy patients
Abstract: For patients with refractory epilepsy, surgery may be a treatment option. While preparing for surgery, brain activity is recorded to delineate the tissue responsible for the seizure and to be resected. In this talk, we consider recordings from subdural grid electrodes with single pulse electrical stimulation (SPES). The responses to SPES consist of physiological early responses (ERs) and pathological delayed responses (DRs).
We start with constructing brain networks with several connectivity measures. We show that ER-based effective connectivity reveals more physiological connections than functional connectivity based on cross-correlation or Granger causality. We find that the epileptogenic zone is a densely connected subnetwork. Second, we model the SPES responses using neural mass models of mesoscopic brain activity. Using dynamical systems theory, we characterize a threshold for DRs to appear and their relevance as a clinical biomarker. Finally, we present preliminary results for fitting large-scale individualized patient networks based on SPES responses.
We are looking forward to welcoming a broad audience and engaging in enriching discussions after the Colloquium talk. Join us in the meeting room from 15:00 for some light refreshments and coffee.
Lenka at International Conference on Applied Mathematics & Computer Science
Published on Aug 8, 2023
Lenka gave an Invited plenary lecture Exploring Synchronization Mechanisms via Bifurcation Analysis at International Conference on Applied Mathematics & Computer Science Lefkada Island, Greece. August 8-10, 2023. You can watch the presentation here.
ModelingUFOs (GAMU interdisciplinary)
Published on Aug 6, 2023
Our team got funding from Grant Agency of Masaryk University for project Mathematical modeling of very and ultra-fast oscillations in EEG signals in cooperation with Faculty of Medicine and CEITEC.
